CIHR Foundation Grants 2016-2017

CIHR Foundation Grants 2016-2017

John Brumell

Hospital for Sick Children

Department of Molecular Genetics

Innate immunity and its disruption by microbial and genetic factors

          4,492,432

Lynne Patricia Howell

Hospital for Sick Children

Department of Biochemistry

Microbial Biofilms: Molecular mechanisms to therapeutics

          3,655,905

Monica J. Justice

Hospital for Sick Children

Department of Molecular Genetics

Pinpointing pathways for pathogenesis and therapeutic intervention by identifying disease modifiers

          2,947,841

Michael D. Taylor

Hospital for Sick Children

Department of Surgery

Heterogeneity through space and time drive the clinical behaviour of childhood medulloblastoma

          4,158,227

Graham L. Collingridge

Sinai Health System

Department of Physiology

Synaptic alterations underlying major brain disorders

          5,554,479

Daniel J. Drucker

Sinai Health System

Department of Medicine

Mechanisms of peptide hormone action: metabolic and therapeutic implications

          4,569,201

Mei Zhen

Sinai Health System

Department of Molecular Genetics

Investigating Mechanisms for Synapse and Circuit Dynamics using the C. elegans Model

          3,013,515

Sharon E. Straus

St. Michael's Hospital

Department of Medicine

Sustaining evidence-based chronic disease management

          3,075,577

Andrea S. Gershon

Sunnybrook Health Sciences Centre

Department of Medicine

Canadian Best Respiratory Research Evaluation and Analyst Team of Health Experts (CanBREATHE)

              962,746

Kullervo H. Hynynen

Sunnybrook Health Sciences Centre

Department of Medical Biophysics

Development of the next generation ultrasound therapy

          2,273,295

Dennis Ko

Sunnybrook Health Sciences Centre

Department of Medicine

Improving Transition of Care and Outcomes of Cardiovascular Disease Using an Innovative Big Data Approach

          2,005,020

Juan C. Zuniga-Pflucker

Sunnybrook Health Sciences Centre

Department of Immunology

Cellular and molecular characterization of T cell development for immune-reconstitution

          2,789,055

Cheryl S. Arrowsmith

University Health Network

Structural Genomics Consortium

Characterization and Modulation of Methylation-Mediated Signaling Networks in Health and Disease

          1,966,469

Robert E. Chen

UHN - Toronto Western Hospital

Department of Medicine

Cortical and basal ganglia mechanisms in movement disorders

          3,268,959

Myron Cybulsky

UHN - Toronto General Hospital

Department of Laboratory Medicine & Pathobiology

Cellular and molecular mechanisms regulating the progression of atherosclerosis: exploiting macrophage reverse transendothelial migration as a therapeutic strategy

          3,246,739

John E. Dick

UHN - Princess Margaret Hospital

Department of Molecular Genetics

Identification and Characterization of Human Hematopoietic and Leukemia Stem Cells and Elucidation of their Role in Regenerative Medicine and Disease

          2,587,536

Mitsuhiko Ikura

UHN - Princess Margaret Hospital

Department of Medical Biophysics

Structural Biology of Calcium-Dependent Cellular Processes in Health and Disease

          2,235,612

Rama Khokha

UHN - Princess Margaret Hospital

Department of Medical Biophysics

MICROENVIRONMENT AND GENETIC DETERMINANTS IN CANCER: Discovering principles in adult tissue stem cells and cancer in breast and bone

          3,037,895

Aaron David Schimmer

UHN - Princess Margaret Hospital

Department of Medicine

Developing new therapeutic strategies for AML (Acute Myeloid Leukemia)

          3,333,379

Gang Zheng

UHN - Princess Margaret Hospital

Department of Medical Biophysics

Porphyrin Nanomedicine for Cancer Imaging and Therapy

          3,300,088

Leah E. Cowen

Campus

Department of Molecular Genetics

Leveraging Essential Genes and Genetic Networks to Cripple Human Fungal Pathogens

          4,122,983

Alan R. Davidson

Campus

Department of Molecular Genetics

Exploring the evolutionary battle between phages and bacteria: from CRISPR-Cas systems to phage-derived antibacterial weapons

          4,141,961

Jack F. Greenblatt

Campus

Donnelly Centre

Human gene expression regulatory mechanisms

          6,135,843

Lewis E. Kay

Campus

Department of Molecular Genetics

Functional Protein Dynamics in Health and Disease

          4,952,455

Beverley A. Orser

Campus

Department of Anesthesia

Targeting GABA-A receptors to mitigate postanesthetic cognitive deficits

          3,579,083

Rachel F. Tyndale

Campus

Department of Pharmacology & Toxicology

Variation in Drug Metabolism and Response

          2,223,982

Mona R. Loutfy

Women's College Hospital

Department of Medicine

The Women and HIV Research Program: Impactful Research with Diverse Women Living with and at Risk of HIV in Canada

          3,780,858

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